4-Phenylmethyl-2-morpholinecarboxylic acid ethyl ester

4-Phenylmethyl-2-morpholinecarboxylic acid ethyl ester - Names and Identifiers

Name	ethyl 4-benzylmorpholine-2-carboxylate
Synonyms	Ethyl4-benzylmorpholine-2-carboxylate Ethyl 4-Benzyl-2-morpholinecarboxylate ethyl 4-benzylmorpholine-2-carboxylate 4-Phenylmethyl-2-morpholinecarboxylic acid ethyl ester 2-Morpholinecarboxylic acid, 4-(phenylmethyl)-, ethyl ester
CAS	135072-32-1 107904-08-5
InChI	InChI=1/C14H19NO3/c1-2-17-14(16)13-11-15(8-9-18-13)10-12-6-4-3-5-7-12/h3-7,13H,2,8-11H2,1H3

4-Phenylmethyl-2-morpholinecarboxylic acid ethyl ester - Physico-chemical Properties

Molecular Formula	C14H19NO3
Molar Mass	249.31
Density	1.128
Boling Point	330.3±37.0 °C(Predicted)
Flash Point	153.577°C
Vapor Presure	0mmHg at 25°C
pKa	5.70±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.531

4-Phenylmethyl-2-morpholinecarboxylic acid ethyl ester - Introduction

Ethyl N-benzylmorpholine-2-carboxylate is an organic compound with the chemical formula C15H15NO3. The following is a description of its nature, use, formulation and safety information:

Nature:
Ethyl N-benzylmorpholine-2-carboxylate is a colorless to pale yellow liquid with a fragrant odor. It is soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons and insoluble in water. The compound has a lower boiling point and a higher melting point.

Use:
N-benzyl morpholine-2-carboxylic acid ethyl ester is mainly used as an intermediate in organic synthesis. It is widely used in the pharmaceutical industry, especially in the synthesis of hormones and drugs. In addition, it can also be used in fields such as pesticides and dyes.

Preparation Method:
The preparation method of N-benzyl morpholine-2-carboxylic acid ethyl ester includes benzylation of morpholine and esterification. Specifically, benzylated morpholine can be obtained by reacting morpholine with benzyl bromide under basic conditions. Then, the obtained benzylmorpholine is reacted with ethyl acetate or isobutanol under acidic conditions to obtain ethyl N-benzylmorpholine-2-carboxylate.

Safety Information:
N-benzyl morpholine-2-carboxylic acid ethyl ester is an organic compound, and it needs to be safe during use or preparation. It can cause irritation and damage to the eyes, skin and respiratory tract. Appropriate protective equipment such as goggles, gloves and respiratory protection should be worn during operation. If exposed to the compound, immediately flush skin or eyes with plenty of water and seek medical attention. In addition, pay attention to avoid contact with the fire source, avoid inhaling its steam.

Last Update：2024-04-09 20:52:54